Laminin and type IV collagen in the human testis
نویسندگان
چکیده
منابع مشابه
Type IV collagen and laminin in Bruch's membrane and basal linear deposit in the human macula.
Tissue obtained from the macula in 10 human eyes (53-77 years) was used for an investigation into the extracellular matrices of the retinal pigment epithelium (RPE), Bruch's membrane, and the choriocapillaris. The ultrastructural distribution of type IV collagen and laminin was documented using immunogold labelling. Labelling for type IV collagen was strongly positive in all the specimens in th...
متن کاملExpression and immunohistochemical localization of laminin and type IV collagen in developing human fetal tracheal glands.
The expression and distribution of laminin and type IV collagen, two major components of the basement membrane, were investigated at the epithelio-mesenchymal interface of the human developing tracheal glands from 10 to 37 weeks of gestation. The localization of these molecules was assessed by indirect immunoperoxidase and indirect immunofluorescence staining and correlated to morphogenesis and...
متن کاملRemodeling of the human endometrial epithelium is regulated by laminin and type IV collagen.
We investigated the expression and function of laminin and type IV collagen (COL-4) in the human endometrial epithelium throughout the menstrual cycle. Their expression was demonstrated by immunohistochemistry, while cytological analysis of the human endometrial epithelial cell line HHUA cultured on laminin- or COL-4-coated plates provided information on their roles in cell proliferation, struc...
متن کاملBinding of laminin to type IV collagen: a morphological study
A mixture of laminin and type IV collagen was analyzed by rotary shadowing using carbon/platinum and electron microscopy. Laminin was found to form distinct complexes with type IV collagen: one site of interaction is located 140 nm from the COOH-terminal, noncollagenous (NC1) domain and the other is located within the NH2-terminal region. The isolated NC1 fragment of type IV collagen does not a...
متن کاملAutocrine/paracrine regulation of human endometrial stromal remodeling by laminin and type IV collagen.
The biological roles of laminin and type IV collagen in human endometrial stromal tissues were investigated by the evaluation of the expression levels in human endometrial tissues using immunohistochemistry. In addition, normal human endometrial stromal cells were cultured in vitro on laminin- or type IV collagen-coated plates and subjected to cytological analyses. Cyclic production of laminin ...
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ژورنال
عنوان ژورنال: International Journal of Andrology
سال: 1985
ISSN: 0105-6263,1365-2605
DOI: 10.1111/j.1365-2605.1985.tb00846.x